Healthy Homocysteine Levels
Activated folate, vitamin B12, B6 and riboflavin provide complementary nutritional support that helps reduce and maintain healthy homocysteine levels.
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A clear look at what this product is designed to support.
Methyl1C BioEnhanced combines activated folate and B vitamins with vitamin C and zinc to provide practitioner-guided support for homocysteine metabolism, cellular energy, neurotransmitter production and healthy nervous-system function.
Activated folate, vitamin B12, B6 and riboflavin provide complementary nutritional support that helps reduce and maintain healthy homocysteine levels.
Activated B vitamins support normal cellular energy production and help maintain healthy everyday energy metabolism.
L-5-MTHF, mecobalamin and P5P support nutrient-dependent pathways involved in normal neurotransmitter synthesis and nervous-system function.
Supports a healthy physiological stress response while helping maintain nervous-system and immune-system health.
A closer look at the formula.
Methyl1C BioEnhanced uses activated forms of folate, B12, B6 and B2 alongside vitamin C and zinc for targeted practitioner support of homocysteine metabolism, energy and neurological function.

Each capsule provides 541mcg levomefolate calcium, equivalent to 500mcg levomefolic acid, an active form of folate used directly within folate-dependent metabolic pathways.

Each capsule provides 500mcg mecobalamin, an active form of vitamin B12 that complements folate in normal homocysteine, nervous-system and cellular metabolic pathways.

Riboflavin sodium phosphate and pyridoxal-5-phosphate provide activated B-vitamin forms to support energy production, neurotransmitter synthesis and healthy nervous-system function.
Orthoplex Methyl1C BioEnhanced is a practitioner-grade activated B-vitamin and mineral formula designed to support healthy homocysteine levels, cellular energy production, neurotransmitter synthesis, nervous-system health, immune function and healthy stress response.
Methyl1C BioEnhanced follows a simple once-daily routine, delivering activated folate and B vitamins with vitamin C and zinc in one practitioner-grade capsule.
Take 1 Methyl1C BioEnhanced capsule for the recommended adult daily dose.
Take the capsule with food and water as part of your regular daily supplement routine.
Use consistently according to your registered healthcare practitioner's recommendation and review any persistent symptoms or changes professionally.
“Methyl1C BioEnhanced combines activated folate, methylated B12, P5P and activated riboflavin with vitamin C and zinc for practitioner-guided support of homocysteine metabolism, energy production, neurotransmitter synthesis and nervous-system health.”
Provides 500mcg active L-5-MTHF equivalent and 500mcg mecobalamin B12 in each capsule for targeted folate- and B12-dependent metabolic support.
Pyridoxal-5-phosphate and riboflavin sodium phosphate provide activated B-vitamin forms to support energy and neurotransmitter pathways.
The combination helps reduce homocysteine levels while supporting healthy nervous-system function, energy production and physiological stress response.
Read experiences shared by customers who have used products from our wellness range.
“My practitioner recommended Methyl1C because I wanted an activated B formula rather than a basic multivitamin. I like that the folate, B12, B6 and B2 forms are all clearly listed.”
Serena L.“I use this as part of the nutritional plan my naturopath set up for me. One capsule with breakfast is easy to remember, and I appreciate that it is a low-excipient vegan formula.”
Michelle T.“A comprehensive activated B formula without needing several separate supplements. I especially like the combination of active folate, methyl B12, P5P, riboflavin and zinc.”
Gabrielle N.Helpful answers about this product, how to use it and what to know before purchasing.