Homocysteine, Energy & Nervous System Support

Orthoplex White Methyl1c BioEnhanced 60 Caps

Regular price $48.75
Activated folate and B-vitamin formula with L-5-MTHF, methylated B12, P5P, activated B2, vitamin C and zinc to help reduce homocysteine levels while supporting energy production, neurotransmitter synthesis, nervous-system health and a healthy stress response.
Activated Folate
Homocysteine Support
Energy Production
Nervous System
Stress Response
Vegan

Always read the label and follow the directions for use.
Curated Wellness
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Why you’ll love it
  • Helps reduce homocysteine levels
  • Supports healthy energy production
  • Aids normal neurotransmitter synthesis
  • Supports a healthy stress response
  • Supports nervous-system health
  • Supports immune-system health
  • Aids protein synthesis
  • Supports healthy growth and development
  • Contains 500mcg active L-5-MTHF per capsule
  • Contains 500mcg mecobalamin B12
  • Provides activated P5P vitamin B6
  • Provides activated riboflavin sodium phosphate
  • Provides 300mg vitamin C
  • Provides 15mg zinc
  • Low-excipient formula
  • Vegan and vegetarian friendly
  • Gluten free
  • Dairy free
  • Soy-protein free
  • Sulfites free
  • Convenient one capsule daily.

Thoughtfully Curated

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Sourced from established health and wellness brands we know and trust.

Clear Product Information

Ingredients, directions and key product details presented clearly in one place.

Fast & Reliable

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Orthoplex White Methyl1c BioEnhanced 60 Caps

Key Benefits

A clear look at what this product is designed to support.

Methyl1C BioEnhanced combines activated folate and B vitamins with vitamin C and zinc to provide practitioner-guided support for homocysteine metabolism, cellular energy, neurotransmitter production and healthy nervous-system function.

Healthy Homocysteine Levels

Activated folate, vitamin B12, B6 and riboflavin provide complementary nutritional support that helps reduce and maintain healthy homocysteine levels.

Energy Production

Activated B vitamins support normal cellular energy production and help maintain healthy everyday energy metabolism.

Neurotransmitter Support

L-5-MTHF, mecobalamin and P5P support nutrient-dependent pathways involved in normal neurotransmitter synthesis and nervous-system function.

Healthy Stress Response

Supports a healthy physiological stress response while helping maintain nervous-system and immune-system health.

Why it works

Ingredient Spotlight

A closer look at the formula.

Methyl1C BioEnhanced uses activated forms of folate, B12, B6 and B2 alongside vitamin C and zinc for targeted practitioner support of homocysteine metabolism, energy and neurological function.

L-5-MTHF Active Folate

L-5-MTHF Active Folate

Each capsule provides 541mcg levomefolate calcium, equivalent to 500mcg levomefolic acid, an active form of folate used directly within folate-dependent metabolic pathways.

Mecobalamin Vitamin B12

Mecobalamin Vitamin B12

Each capsule provides 500mcg mecobalamin, an active form of vitamin B12 that complements folate in normal homocysteine, nervous-system and cellular metabolic pathways.

Activated B2 + P5P B6

Activated B2 + P5P B6

Riboflavin sodium phosphate and pyridoxal-5-phosphate provide activated B-vitamin forms to support energy production, neurotransmitter synthesis and healthy nervous-system function.

Product Information

Everything you need to know

Orthoplex Methyl1C BioEnhanced is a practitioner-grade activated B-vitamin and mineral formula designed to support healthy homocysteine levels, cellular energy production, neurotransmitter synthesis, nervous-system health, immune function and healthy stress response.

500mcg active L-5-MTHF
500mcg methylated B12
Activated B2 + P5P B6
1 capsule daily with food
“Activated nutritional support for healthy homocysteine metabolism, energy production and nervous-system function.”
Key Ingredients ⌄

Each capsule contains:

  • Levomefolate calcium — 541mcg
  • Equivalent Levomefolic acid / active L-5-MTHF — 500mcg
  • Mecobalamin — 500mcg
  • Ascorbic acid — 300mg
  • Vitamin C — 300mg
  • Zinc — 15mg
  • From zinc citrate
  • Pyridoxal-5-phosphate monohydrate — 23.6mg
  • Equivalent Pyridoxine / Vitamin B6 — 15.1mg
  • Riboflavin sodium phosphate — 29.9mg
  • Equivalent Riboflavin / Vitamin B2 — 21.9mg
How to Take ⌄

Adults: Take 1 capsule daily with food, or as recommended by your registered healthcare practitioner.

Warnings ⌄
  • Contains vitamin B6.
  • Stop taking this product and see your healthcare practitioner as soon as possible if you experience tingling, burning or numbness.
  • Contains zinc, which may be harmful if taken in large amounts or for a prolonged period.
  • Vitamin and mineral supplements should not replace a balanced diet.
  • If symptoms persist, consult your healthcare professional.
  • Use according to your registered healthcare practitioner's recommendations.
  • If taking prescription medicines or other high-dose B-vitamin products, review the complete regimen with your healthcare practitioner.
  • Always read the label and follow the directions for use.
  • Store below 30°C in a cool, dry place away from direct sunlight.
  • Keep out of reach of children.
Allergens & Dietary Information ⌄

Suitable for:

  • Vegan diets
  • Vegetarian diets

BioConcepts lists Methyl1C BioEnhanced as:

  • Gluten free
  • Dairy free
  • Soy-protein free
  • Sulfites free

Incidental excipients: Nil.

How to Use

Simple and straightforward

Methyl1C BioEnhanced follows a simple once-daily routine, delivering activated folate and B vitamins with vitamin C and zinc in one practitioner-grade capsule.

Always follow the label and practitioner guidance.
1

Take One Capsule

Take 1 Methyl1C BioEnhanced capsule for the recommended adult daily dose.

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2

Take With Food

Take the capsule with food and water as part of your regular daily supplement routine.

›
3

Use as Practitioner Directed

Use consistently according to your registered healthcare practitioner's recommendation and review any persistent symptoms or changes professionally.

›
Practitioner Guidance

A practitioner-led approach

“Methyl1C BioEnhanced combines activated folate, methylated B12, P5P and activated riboflavin with vitamin C and zinc for practitioner-guided support of homocysteine metabolism, energy production, neurotransmitter synthesis and nervous-system health.”

Victoria O'Sullivan
Victoria O'Sullivan Naturopath

Activated Folate + B12

Provides 500mcg active L-5-MTHF equivalent and 500mcg mecobalamin B12 in each capsule for targeted folate- and B12-dependent metabolic support.

P5P + Activated B2

Pyridoxal-5-phosphate and riboflavin sodium phosphate provide activated B-vitamin forms to support energy and neurotransmitter pathways.

Homocysteine + Nervous System

The combination helps reduce homocysteine levels while supporting healthy nervous-system function, energy production and physiological stress response.

What Our Customers Say

Real reviews. Real experiences.

Read experiences shared by customers who have used products from our wellness range.

★★★★★

“My practitioner recommended Methyl1C because I wanted an activated B formula rather than a basic multivitamin. I like that the folate, B12, B6 and B2 forms are all clearly listed.”

Serena L.
✓ Verified Purchase
★★★★★

“I use this as part of the nutritional plan my naturopath set up for me. One capsule with breakfast is easy to remember, and I appreciate that it is a low-excipient vegan formula.”

Michelle T.
✓ Verified Purchase
★★★★★

“A comprehensive activated B formula without needing several separate supplements. I especially like the combination of active folate, methyl B12, P5P, riboflavin and zinc.”

Gabrielle N.
✓ Verified Purchase
Frequently Asked Questions

Got a question?

Helpful answers about this product, how to use it and what to know before purchasing.

What is Orthoplex Methyl1C BioEnhanced designed to support?⌄

Methyl1C BioEnhanced is formulated to help reduce homocysteine levels while supporting energy production, neurotransmitter synthesis, healthy stress response, nervous-system and immune-system health, protein synthesis and general wellbeing.

What form of folate is in Methyl1C BioEnhanced?⌄

Each capsule contains 541mcg levomefolate calcium, equivalent to 500mcg levomefolic acid, an active L-5-MTHF form of folate.

What form of vitamin B12 does the current formula contain?⌄

The current formula contains 500mcg mecobalamin, also known as methylcobalamin. Older versions also contained hydroxocobalamin, but that ingredient is not present in the current ARTG 511718 formula.

How do I take Methyl1C BioEnhanced?⌄

Adults take 1 capsule daily with food, or follow their registered healthcare practitioner's recommendation. A 60-capsule bottle provides approximately 60 days at the standard dose.

Is Methyl1C BioEnhanced vegan and gluten free?⌄

Yes. BioConcepts lists the current formula as vegan and vegetarian friendly, gluten free, dairy free, soy-protein free and sulfites free.